For their research, the young scientists will use various imaging methods, which will enable them to most precisely monitor the behaviour of magnesium implants during the process of bio-compatible degradation. Biodegradable implants offer many benefits, for example for patients needing trauma or orthopaedic intervention (e.g. to fix fractures) because a second surgery to remove the metal implants after successful healing can be avoided. The participating scientists and representatives from industry meet for the first time at the kick-off meeting of the "MgSafe" network in Hamburg on 6 November 2018.
Prof. Dr. Regine Willumeit-Römer, coordinator of the project and Head of the Metallic Biomaterials Division at the Helmholtz Zentrum in Geesthacht, explains: "Biomedical imaging is fundamental to both diagnosis and therapy, because we need to monitor the behaviour of the degrading implant materials. There is still need for improvement as far as the new class of biodegradable magnesium-based implants is concerned. In the MgSafe project, we will establish new techniques while educating 15 PhD students interdisciplinary in both imaging and implant technologies. All in a cross-disciplinary manner."
Apart from pursuing scientific development, the European Marie Skłodowska Curie networks aim at training highly talented doctoral students by providing them a framework of excellent research projects in an international environment. To this end, 15 junior scientists will begin their doctoral studies at the universities of Graz, Gothenburg, Hamburg, Hanover, Oslo, Pisa, and Warsaw in April of 2019. Their main target is to investigate the human body's reaction to the implant and monitor the behaviour of the material during magnesium degradation – with an unequalled degree of precision and Detail.
The MSCA PhD students will be trained in interdisciplinary issues during workshops and spend secondments with the project partners to gain comprehensive knowledge in their research fields, which they will benefit from for their future scientific qualification.
Ultimately, the work of this ambitious research network is expected to result in the development of new implant products. The new combination of imaging technologies developed within the project is a prerequisite for the desired increase in patient safety. The MSCA projects primarily follow an industry-oriented approach and, consequently, they significantly contribute to strengthening the correlation between academic and industrial Research.
The Partners of the MgSafe project
- Helmholtz-Zentrum Geesthacht for Materials and Coastal Research, Metallic Biomaterials Department (Geesthacht, Germany)
- National Research Council (CNR) Institute of clinical physiology (IFC) (Pisa, Italy)
- Medical University of Graz, Department of Orthopaedics and Orthopaedic Surgery (Graz, Austria)
- University of Oslo, Department of Biomaterial (Oslo, Norway)
- Oslo Metropolitan University, Faculty of Technology, Art, and Design (Oslo, Norway)
- Hanover Medical School (Hanover, Germany)
- University of Gothenburg, Sahlgrenska Academy (Gothenburg, Sweden)
- Warsaw University of Technology (Warsaw, Poland)
- MRITools GmbH (Berlin, Germany)
- Syntellix AG (Hanover, Germany)
- Scanco Medical AG (Brüttisellen, Switzerland)
- Fujifilm Sonosite B.V (Amsterdam, Netherlands)
- BRI.Tech BioResorbable Implant Technologies (Graz, Austria)
